8-Hydroxy-5-deazaflavin:NADPH oxidoreductase (EC 1.5.1.40, 8-OH-5dFl:NADPH oxidoreductase) is an enzyme with systematic name reduced coenzyme F420:NADP+ oxidoreductase.[1] This enzyme catalyses the following chemical reaction
| 8-hydroxy-5-deazaflavin:NADPH oxidoreductase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.5.1.40 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
- reduced coenzyme F420 + NADP+ coenzyme F420 + NADPH + H+
The enzyme requires the 5-deazaflavin structure, as well as an 8-hydroxy group in the substrate.
References
edit- ^ Eker AP, Hessels JK, Meerwaldt R (January 1989). "Characterization of an 8-hydroxy-5-deazaflavin:NADPH oxidoreductase from Streptomyces griseus". Biochimica et Biophysica Acta (BBA) - General Subjects. 990 (1): 80–6. doi:10.1016/s0304-4165(89)80015-7. PMID 2492438.
External links
edit- 8-hydroxy-5-deazaflavin:NADPH+oxidoreductase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
