8-oxoguanine deaminase (EC 3.5.4.32, 8-OGD) is an enzyme with systematic name 8-oxoguanine aminohydrolase.[1] This enzyme catalyses the following chemical reaction
| 8-oxoguanine deaminase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 3.5.4.32 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
- 8-oxoguanine + H2O urate + NH3
Zn2+ is bound in the active site.
References
edit- ^ Hall RS, Fedorov AA, Marti-Arbona R, Fedorov EV, Kolb P, Sauder JM, Burley SK, Shoichet BK, Almo SC, Raushel FM (February 2010). "The hunt for 8-oxoguanine deaminase". Journal of the American Chemical Society. 132 (6): 1762–3. doi:10.1021/ja909817d. PMC 2820149. PMID 20088583.
External links
edit- 8-oxoguanine+deaminase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
