Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase (EC 2.4.1.145, N-acetylglucosaminyltransferase IV, N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IV, beta-acetylglucosaminyltransferase IV, uridine diphosphoacetylglucosamine-glycopeptide beta4-acetylglucosaminyltransferase IV, alpha-1,3-mannosylglycoprotein beta-1,4-N-acetylglucosaminyltransferase, GnTIV) is an enzyme with systematic name UDP-N-acetyl-D-glucosamine:3-(2-(N-acetyl-beta-D-glucosaminyl)-alpha-D-mannosyl)-glycoprotein 4-beta-N-acetyl-D-glucosaminyltransferase.[1] This enzyme catalyses the following chemical reaction
| Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.4.1.145 | ||||||||
| CAS no. | 86498-16-0 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
- UDP-N-acetyl-D-glucosamine + 3-(2-[N-acetyl-beta-D-glucosaminyl]-alpha-D-mannosyl)-beta-D-mannosyl-R UDP + 3-(2,4-bis[N-acetyl-beta-D-glucosaminyl]-alpha-D-mannosyl)-beta-D-mannosyl-R
R represents the remainder of the N-linked oligosaccharide in the glycoprotein acceptor.
References
editExternal links
edit- Alpha-1,3-mannosyl-glycoprotein+4-beta-N-acetylglucosaminyltransferase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
