Adenylyl cyclase type 6 is an enzyme that in humans is encoded by the ADCY6 gene.[5]

ADCY6
Identifiers
AliasesADCY6, AC6, LCCS8, adenylate cyclase 6
External IDsOMIM: 600294; MGI: 87917; HomoloGene: 22400; GeneCards: ADCY6; OMA:ADCY6 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_015270
NM_020983
NM_001390830
NM_001390831

NM_007405
NM_001368413

RefSeq (protein)

NP_056085

NP_031431
NP_001355342

Location (UCSC)Chr 12: 48.77 – 48.79 MbChr 15: 98.49 – 98.51 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Function

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This gene encodes adenylyl cyclase 6, which is a membrane-associated enzyme and catalyzes the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). The expression of this gene is found in normal thyroid and brain tissues, as well as some tumors; and its expression is significantly higher in one hyperfunctioning thyroid tumor than in normal thyroid tissue. Alternative splicing generates 2 transcript variants.[5]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000174233Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000022994Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b "Entrez Gene: ADCY6 adenylate cyclase 6".
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Further reading

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