AREsite is a database of AU-rich elements (ARE) in vertebrate mRNA 3'-untranslated regions (UTRs).[1] AU-rich elements are involved in the control of gene expression. They are the most common determinant of RNA stability in mammalian cells. The most recent version of AREsite is called AREsite 2.[2] It represents an update that allows for more detailed analysis of ARE, GRE, and URE (AU, GU, and U-rich elements).
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Description | comprehensive investigation of AU-rich elements. |
Contact | |
Research center | University of Vienna |
Primary citation | PMID 21071424 |
Release date | 2010 |
Access | |
Website | rna |
See also
editReferences
edit- ^ Gruber, Andreas R; Fallmann Jörg; Kratochvill Franz; Kovarik Pavel; Hofacker Ivo L (Jan 2011). "AREsite: a database for the comprehensive investigation of AU-rich elements". Nucleic Acids Res. 39 (Database issue). England: D66–69. doi:10.1093/nar/gkq990. PMC 3013810. PMID 21071424.
- ^ Fallmann, Jörg; Sedlyarov, Vitaly; Tanzer, Andrea; Kovarik, Pavel; Hofacker, Ivo L. (2016-01-04). "AREsite2: an enhanced database for the comprehensive investigation of AU/GU/U-rich elements". Nucleic Acids Research. 44 (Database issue): D90–D95. doi:10.1093/nar/gkv1238. ISSN 0305-1048. PMC 4702876. PMID 26602692.