Apoptosis-related protein 3 is a protein that in humans is encoded by the ATRAID gene .[ 5] [ 6] [ 7]
This gene is thought to be involved in apoptosis , and may also be involved in hematopoietic development and differentiation. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.[ 7]
^ a b c GRCh38: Ensembl release 89: ENSG00000138085 – Ensembl , May 2017
^ a b c GRCm38: Ensembl release 89: ENSMUSG00000013622 – Ensembl , May 2017
^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ Zhang QH, Ye M, Wu XY, Ren SX, Zhao M, Zhao CJ, Fu G, Shen Y, Fan HY, Lu G, Zhong M, Xu XR, Han ZG, Zhang JW, Tao J, Huang QH, Zhou J, Hu GX, Gu J, Chen SJ, Chen Z (Nov 2000). "Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells" . Genome Res . 10 (10): 1546–60. doi :10.1101/gr.140200 . PMC 310934 . PMID 11042152 .
^ Zhu F, Yan W, Zhao ZL, Chai YB, Lu F, Wang Q, Peng WD, Yang AG, Wang CJ (Nov 2000). "Improved PCR-based subtractive hybridization strategy for cloning differentially expressed genes" . BioTechniques . 29 (2): 310–3. doi :10.2144/00292st06 . PMID 10948432 .
^ a b "Entrez Gene: C2orf28 chromosome 2 open reading frame 28" .
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Yang G, Yu F, Fu H, et al. (2007). "Identification of the distinct promoters for the two transcripts of apoptosis related protein 3 and their transcriptional regulation by NFAT and NFkappaB". Mol. Cell. Biochem . 302 (1–2): 187–94. doi :10.1007/s11010-007-9440-7 . PMID 17387583 . S2CID 1525070 .
Yu F, Yang G, Zhao Z, et al. (2007). "Apoptosis related protein 3, an ATRA-upregulated membrane protein arrests the cell cycle at G1/S phase by decreasing the expression of cyclin D1". Biochem. Biophys. Res. Commun . 358 (4): 1041–6. doi :10.1016/j.bbrc.2007.05.049 . PMID 17524364 .