Abecassis or Abécassis or Abecasis (Hebrew: אבוקסיס, אבקסיס) is a Sephardic patronymic most commonly found among Moroccan Jews.
Notable people with the surname include:
- Eliette Abécassis (born 1969), French writer
- Eryck Abecassis (born 1956), French composer and musician
- George Abecassis (1913–1991), English race driver
- Gonçalo Abecasis (born 1976), Portuguese genetic epidemiologist
- Ricardo Abecassis Espírito Santo Silva, Portuguese financier and former Board Member at Banco Espírito Santo
- Yael Abecassis (born 1967), Israeli actress