Aceglatone (Glucaron) is an antineoplastic drug available in Japan.[2]
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Trade names | Glucaron |
Other names | D-Glucaric acid di-γ-lactone 2,5-diacetate 2,5-Di-O-acetyl-D-glucaro-1,4:6,3-dilactone 2,5-Di-O-acetyl-D-glucosaccharo-1,4:6,3-dilactone |
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Formula | C10H10O8 |
Molar mass | 258.182 g·mol−1 |
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Melting point | 185 to 186 °C (365 to 367 °F) [1] |
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It is an inhibitor of the enzyme β-glucuronidase.[3]
References
edit- ^ Merck Index, 11th Edition, 20
- ^ Glucaron, drugs.com
- ^ Iida R, Nagata S, Kakimoto M, Akaike H, Watanabe H, Shioya A (1965). "2,5-Di-O-acetyl-D-glucosaccharo-(1→4)(6→3)-dilactone, a new potent β-glucuronidase inhibitor". Japanese Journal of Pharmacology. 15 (1): 88–90. doi:10.1254/jjp.15.88. PMID 14348597.