Acridone alkaloids are natural products derived from acridone.[1]
Occurrence
editAcridone alkaloids are found in bark, wood, leaves and roots of rue plants,[1] especially in roots and suspension cultures of rue.[2]
Examples
editThis group is named after the acridone. Further members are acronycin, melicopicine and rutacridone, among others:[1][3]
Acronycin
Melicopicine
Rutacridon
Properties
editMany acridone alkaloids are methylated on the nitrogen atom and also have two oxygen functional groups, which can be free, alkylated or incorporated into rings. Acridone alkaloids show a blue-green fluorescence so that they can be detected with UV light. Some alkaloids of this group are effective against malaria pathogens. Furthermore, acronycin inhibits cell division.[2]
References
edit- ^ a b c Entry on Acridone. at: Römpp Online. Georg Thieme Verlag, retrieved 21 April 2020.
- ^ a b R. Hänsel, O.Sticher (2007), Pharmakognosie Phytopharmazie (in German) (8 ed.), Heidelberg: Springer Medizin Verlag, pp. 101,1326, ISBN 9783540265085
- ^ "Acridone alkaloid biosynthesis". Archived from the original on 12 June 2020. Retrieved 22 April 2020.