In enzymology, an acylglycerol kinase (EC 2.7.1.94) is an enzyme that catalyzes the chemical reaction
acylglycerol kinase | |||||||||
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Identifiers | |||||||||
EC no. | 2.7.1.94 | ||||||||
CAS no. | 62213-37-0 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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- ATP + acylglycerol ADP + acyl-sn-glycerol 3-phosphate
The two substrates of this enzyme are ATP and acylglycerol, whereas its two products are ADP and acyl-sn-glycerol 3-phosphate.
This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is ATP:acylglycerol 3-phosphotransferase. Other names in common use include monoacylglycerol kinase, monoacylglycerol kinase (phosphorylating), sn-2-monoacylglycerol kinase, MGK, monoglyceride kinase, and monoglyceride phosphokinase. This enzyme participates in glycerolipid metabolism.
References
edit- Pieringer RA, Hokin LE (March 1962). "Biosynthesis of lysophosphatdic acid from monoglyceride and adenosine triphosphate". The Journal of Biological Chemistry. 237: 653–8. PMID 14486486.
- Pieringer RA, Kunnes RS (July 1965). "The biosynthesis of phosphatidic acid and lysophosphatidic acid by glyceride phosphokinase pathways in Escherichia coli" (PDF). The Journal of Biological Chemistry. 240 (7): 2833–8. PMID 14342303.