Albumin I

Available protein structures:
Pfam	structures / ECOD
PDB	RCSB PDB; PDBe; PDBj
PDBsum	structure summary

Albumin_I
Albumin_I
	Solution structure of PA1b. PDB entry 1p8b
Identifiers
Symbol	Albumin_I
Pfam	PF08027
Pfam clan	CL0083
InterPro	IPR012512
Pfam
Available protein structures:
Pfam	structures / ECOD
PDB	RCSB PDB; PDBe; PDBj
PDBsum	structure summary

Albumin I (PA1b) is a hormone-like peptide found in the seeds of legumes such as the pea plant (Pisum sativum)^[2] or soya bean (Glycine max)^[3] which have been shown to have insecticidal properties.^[2] It stimulates kinase activity upon binding a membrane bound 43 kDa receptor within the plant which affects cell proliferation.^[3] The structure reveals an inhibitor cystine knot (knottin)-like fold, comprising three beta strands.^[1]^[2]

References

^ ^a ^b Jouvensal, L.; Quillien, L.; Ferrasson, E.; Rahbé, Y.; Guéguen, J.; Vovelle, F. O. (2003). "PA1b, an Insecticidal Protein Extracted from Pea Seeds (Pisum sativum): 1H-2-D NMR Study and Molecular Modeling†,‡". Biochemistry. 42 (41): 11915–11923. doi:10.1021/bi034803l. PMID 14556622.
^ ^a ^b ^c Da Silva, P.; Rahioui, I.; Laugier, C.; Jouvensal, L.; Meudal, H.; Chouabe, C.; Delmas, A. F.; Gressent, F. (2010). "Molecular Requirements for the Insecticidal Activity of the Plant Peptide Pea Albumin 1 Subunit b (PA1b)". Journal of Biological Chemistry. 285 (43): 32689–32694. doi:10.1074/jbc.M110.147199. PMC 2963353. PMID 20660598.
^ ^a ^b Yamazaki T, Takaoka M, Katoh E, Hanada K, Sakita M, Sakata K, Nishiuchi Y, Hirano H (March 2003). "A possible physiological function and the tertiary structure of a 4-kDa peptide in legumes". Eur. J. Biochem. 270 (6): 1269–76. doi:10.1046/j.1432-1033.2003.03489.x. PMID 12631285.

This article incorporates text from the public domain Pfam and InterPro: IPR012512