In enzymology, an alginate synthase (EC 2.4.1.33) is an enzyme that catalyzes the chemical reaction

alginate synthase
Identifiers
EC no.2.4.1.33
CAS no.37257-31-1
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins
GDP-D-mannuronate + (alginate)n GDP + (alginate)n+1

Thus, the two substrates of this enzyme are GDP-D-mannuronate and (alginate)n, whereas its two products are GDP and (alginate)n+1.

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is GDP-D-mannuronate:alginate D-mannuronyltransferase. This enzyme is also called mannuronosyl transferase. This enzyme participates in fructose and mannose metabolism.

References

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  • Lin TY, Hassid WZ (1966). "Pathway of algnic acid synthesis in the marine brown alga, Fucus gardneri Silva". J. Biol. Chem. 241 (22): 5284–97. PMID 5954796.