Allokutzneria albata is a bacterium from the genus Allokutzneria which has been isolated from soil from the Mindanao Island on the Philippines.[1][2][4][5] Allokutzneria albata produces the antivirals cycloviracin B1 and cycloviracin B2[6][7] as well as the antibiotic sequanamycin A (SEQ-503), a 14-membered ring erythromycin family macrolide against Mycobacterium tuberculosis, which was discovered in 1969.[8]

Allokutzneria albata
Scientific classification Edit this classification
Domain: Bacteria
Phylum: Actinomycetota
Class: Actinomycetia
Order: Pseudonocardiales
Family: Pseudonocardiaceae
Genus: Allokutzneria
Species:
A. albata
Binomial name
Allokutzneria albata
(Tomita et al. 1993) Labeda and Kroppenstedt 2008[1]
Type strain[2][3]
ATCC 55061
CGMCC 4.1881
DSM 44149
JCM 9917
KCTC 9837
NBRC 101910
NCIMB 13433
NRRL B-24461
R-761-7
SA-27176
Synonyms

References

edit
  1. ^ a b Labeda, D. P.; Kroppenstedt, R. M. (1 June 2008). "Proposal for the new genus Allokutzneria gen. nov. within the suborder Pseudonocardineae and transfer of Kibdelosporangium albatum Tomita et al. 1993 as Allokutzneria albata comb. nov". International Journal of Systematic and Evolutionary Microbiology. 58 (6): 1472–1475. doi:10.1099/ijs.0.65474-0. PMID 18523197.
  2. ^ a b Parte, A.C. "Allokutzneria". LPSN.
  3. ^ "Allokutzneria albata Taxon Passport – StrainInfo". www.straininfo.net. Archived from the original on 2017-08-13. Retrieved 2017-08-13.
  4. ^ Parker, Charles Thomas; Wigley, Sarah; Garrity, George M (2009). Parker, Charles Thomas; Garrity, George M (eds.). "Nomenclature Abstract for Allokutzneria albata (Tomita et al. 1993) Labeda and Kroppenstedt 2008". The NamesforLife Abstracts. doi:10.1601/nm.13027.
  5. ^ "Details: DSM-44149". www.dsmz.de.
  6. ^ Tomita, K.; Hoshino, Y.; Miyaki, T. (1 April 1993). "Kibdelosporangium albatum sp. nov., Producer of the Antiviral Antibiotics Cycloviracins". International Journal of Systematic Bacteriology. 43 (2): 297–301. doi:10.1099/00207713-43-2-297. PMID 8494740.
  7. ^ Tsunakawa, M; Komiyama, N; Tenmyo, O; Tomita, K; Kawano, K; Kotake, C; Konishi, M; Oki, T (September 1992). "New antiviral antibiotics, cycloviracins B1 and B2. I. Production, isolation, physico-chemical properties and biological activity". The Journal of Antibiotics. 45 (9): 1467–71. doi:10.7164/antibiotics.45.1467. PMID 1331014.
  8. ^ Zhang, Jidong; Lair, Christine; Roubert, Christine; Amaning, Kwame; Barrio, María Belén; Benedetti, Yannick; Cui, Zhicheng; Xing, Zhongliang; Li, Xiaojun; Franzblau, Scott G.; Baurin, Nicolas; Bordon-Pallier, Florence; Cantalloube, Cathy; Sans, Stephanie; Silve, Sandra (2023-03-02). "Discovery of natural-product-derived sequanamycins as potent oral anti-tuberculosis agents". Cell. 186 (5): 1013–1025.e24. doi:10.1016/j.cell.2023.01.043. ISSN 0092-8674. PMC 9994261. PMID 36827973.