α-Eudesmol synthase (EC 4.2.3.85) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase (α-eudesmol-forming).[1] This enzyme catalyses the following chemical reaction
| α-eudesmol synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 4.2.3.85 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
- (2E,6E)-farnesyl diphosphate + H2O α-eudesmol + diphosphate
The recombinant enzyme from ginger (Zingiber zerumbet) gives β-eudesmol, 10-epi-γ-eudesmol, α-eudesmol and aristolene.
References
edit- ^ Yu F, Harada H, Yamasaki K, Okamoto S, Hirase S, Tanaka Y, Misawa N, Utsumi R (March 2008). "Isolation and functional characterization of a β-eudesmol synthase, a new sesquiterpene synthase from Zingiber zerumbet Smith". FEBS Letters. 582 (5): 565–72. doi:10.1016/j.febslet.2008.01.020. PMID 18242187.
External links
edit- Alpha-eudesmol+synthase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
