α-Santalene synthase (EC 4.2.3.82) is an enzyme with systematic name (2E,6E)-farnesyl diphosphate lyase (cyclizing, (+)-α-santalene-forming).[1] This enzyme catalyses the following chemical reaction
| α-santalene synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 4.2.3.82 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
- (2E,6E)-farnesyl diphosphate (+)-α-santalene + diphosphate
The enzyme synthesizes a mixture of sesquiterpenes.
References
edit- ^ Jones CG, Moniodis J, Zulak KG, Scaffidi A, Plummer JA, Ghisalberti EL, Barbour EL, Bohlmann J (May 2011). "Sandalwood fragrance biosynthesis involves sesquiterpene synthases of both the terpene synthase (TPS)-a and TPS-b subfamilies, including santalene synthases". The Journal of Biological Chemistry. 286 (20): 17445–54. doi:10.1074/jbc.m111.231787. PMC 3093818. PMID 21454632.
External links
edit- Alpha-santalene+synthase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
