Alpha-santalene synthase

α-Santalene synthase (EC 4.2.3.82) is an enzyme with systematic name (2E,6E)-farnesyl diphosphate lyase (cyclizing, (+)-α-santalene-forming).[1] This enzyme catalyses the following chemical reaction

α-santalene synthase
Identifiers
EC no.4.2.3.82
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
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PMCarticles
PubMedarticles
NCBIproteins
(2E,6E)-farnesyl diphosphate (+)-α-santalene + diphosphate

The enzyme synthesizes a mixture of sesquiterpenes.

References

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  1. ^ Jones CG, Moniodis J, Zulak KG, Scaffidi A, Plummer JA, Ghisalberti EL, Barbour EL, Bohlmann J (May 2011). "Sandalwood fragrance biosynthesis involves sesquiterpene synthases of both the terpene synthase (TPS)-a and TPS-b subfamilies, including santalene synthases". The Journal of Biological Chemistry. 286 (20): 17445–54. doi:10.1074/jbc.m111.231787. PMC 3093818. PMID 21454632.
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