Angela Tamagnini was a pioneer in the use of smallpox vaccination in Portugal. She also became famous for her role in resisting the French invasion of the city of Tomar in the Santarém District of Portugal during the Napoleonic Wars.[1]

Angela Tamagnini
Born(1770-10-26)26 October 1770
Died2 July 1827(1827-07-02) (aged 56)
Tomar, Portugal
NationalityItalian; Portuguese
OccupationVaccinologist
Known forMediating with French troops to stop invasion of Tomar during the Peninsular War

Biography

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Angela Tamagnini was born in Milan, Italy on 26 October 1770. She moved to Portugal in 1783 together with her uncle, Inácio Francisco Tamagnini, who became the doctor of Queen Maria I.

In 1795, she married António Florêncio de Abreu e Andrade, son of a rich tobacco and soap trader. Her husband died in 1806.[1][2][3] She had one son, João. Her great-grandson was Fernando Tamagnini de Abreu e Silva, the commander of the Portuguese Expeditionary Corps, which fought with the Allies during World War I.

During the Peninsular War, in June 1808, the year after the French invasion of Portugal under General Junot, the Portuguese in the northwest of the country rebelled. French troops led by General Margaron were sent to quell the uprising in Tomar. It was clear that the defence of Tomar would be hopeless and Tamagnini, who knew how to speak French, was asked to act as an intermediary between the city and the French in order to negotiate a peaceful surrender, thereby avoiding potential plundering and other atrocities. She succeeded in avoiding destruction of the city, reducing the reparations expected by the French, and saving the lives of three Portuguese friars who were to be executed.[1][2][3][4]

Together with Maria Isabel Wittenhall van Zeller (1749–1819), who was active in the Porto area of Portugal,[5] Tamagnini was a female pioneer in the use of vaccinations against smallpox. Previously the disease had been treated by inoculation, also known as variolation, which involved the deliberate introduction of material from smallpox pustules into the skin. This induced immunity to smallpox but generally also produced a mild form of the infection. Towards the end of the 18th century, the work of Edward Jenner and others showed that cowpox delivered by vaccination to humans could protect against smallpox.[6][7] Tamagnini ordered everything necessary for the vaccine’s preparation and application from the United Kingdom, and provided it to the Vaccine Institute established in Coimbra by the Royal Academy of Sciences. She, herself, carried out vaccinations in Tomar at her own expense. Tamagnini was appointed a Correspondent of the Vaccine Institute in 1812 but, unlike Wittenhall van Zeller, was not awarded a Gold Medal by the Institute because she failed to provide the necessary data.[2][3][8]

Death and legacy

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Tamagnini died in Tomar on 2 July 1827. In Tomar, she is honoured by having one of the city’s major roads named after her.[3]

References

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  1. ^ a b c "Personagens de Tomar". História de Tomar. Retrieved 15 June 2020.
  2. ^ a b c Carvalho,Lopes de, A.M.; Graça, Luís (2008). Notícia biográfica de D.Angela Tamagnini D'Abreu (2nd ed.). Tomar: Câmara Municipal de Tomar. ISBN 978-972-99726-2-1.
  3. ^ a b c d "Ângela Tamagnini, uma estrangeira na Toponímia de: Tomar". Ruas com história. 29 April 2017. Retrieved 15 June 2020.
  4. ^ "Ângela Caetana Maria Tamagnini nasceu em Milão a 26 de Outubro de 1770" (PDF). Archived from the original (PDF) on 15 June 2020. Retrieved 15 June 2020.
  5. ^ Seabra van Zeller, Ana Maria (2004). "Maria Isabel Witenhall van Zeller". British Historical Society of Portugal. 31: 117. Retrieved 29 May 2020.
  6. ^ Williams, Gareth (2010). Angel of Death: The Story of Smallpox. Basingstoke: Palgrave Macmillan. ISBN 9780230274716.
  7. ^ Riedel, Stefan (2005). "Edward Jenner and the history of smallpox and vaccination". Proceedings (Baylor University. Medical Center). 18 (1): 21–25. doi:10.1080/08998280.2005.11928028. PMC 1200696. PMID 16200144.
  8. ^ Teixeira Rebelo da Silva, José Alberto. "A Academia Real das Ciências de Lisboa (1779-1834): ciências e hibridismo numa periferia europeia" (PDF). University of Lisbon. Retrieved 29 May 2020.