Wikipedia

Annettee Nakimuli

Annettee Olivia Nakimuli is a Ugandan obstetrician, gynecologist, medical researcher, academic and academic administrator. Since 17 February 2021, she serves as the Dean of Makerere University School of Medicine, the oldest medical school in East Africa. She concurrently serves as the Head of Department of Obstetrics and Gynecology at the same medical school, a role she has served in since 2016.[1] She is also the President of the East, Central and Southern Africa College of Obstetrics and Gynecology.[2]

Annettee Olivia Nakimuli
Born1975 (age 48–49)
Uganda
NationalityUgandan
CitizenshipUganda
EducationMakerere University
(Bachelor of Medicine and Bachelor of Surgery)
(Master of Medicine in Obstetrics and Gynecology)
(Doctor of Philosophy in Obstetrics and Gynecology)
Occupation(s)Obstetrician, Gynecologist, Researcher, Academic
Years active2000–present
Known forMedical practice & research
TitleHead of Obstetrics and Gynecology and Dean
Makerere University School of Medicine
President of the East, Central and Southern Africa College of Obstetrics and Gynecology

Background and education

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She was born in the Buganda Region of Uganda. After attending primary and secondary schools, she was admitted to Makerere University to study human medicine. Her first degree was the Bachelor of Medicine and Bachelor of Surgery (MBChB). Her Master of Medicine in Obstetrics and Genecology (MMed Obs & Gyn) was also obtained from Makerere. Later, she was awarded a Doctor of Philosophy (PhD) degree by Makerere University in collaboration with the University of Cambridge.[3] Her dissertation for the PhD thesis was titled "The Role of Natural Killer Cells in Pre-eclampsia in an African Population".[4]

Career

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Nakimuli is a clinical researcher in complications of pregnancy, with focus on pre-eclampsia and eclampsia among sub-Saharan African women. Her work, with collaborators from the University of Cambridge identified a genetic locus, associated with protection from developing pre-eclampsia (Nakimuli et al., PNAS 2015). This genetic region has only been described among people of African ancestry. More work in this area is ongoing.[3]

She has published widely in peer-reviewed publications and has in excess of 65 publications to her name.[5]

Other responsibilities

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In her capacity as the dean of the school of medicine at Makerere University Medical School, within Makerere University College of Health Sciences, Nakimuli concurrently serves as the head of department of obstetrics and gynecology at the same medical school. She is also a consultant in obstetrics and gynecology at Mulago National Referral Hospital, the teaching hospital of Makerere University School of Medicine.[3]

She serves on several international and national committees, including:[3]

  • She previously served as the Vice President of the East Central and Southern Africa College of Obstetrics and Gynaecology (ECSACOG) which was established in 2017".[3]

Recent developments

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During the fourth quarter of calendar year 2021, Associate Professor Nakimuli was awarded a five-year research grant worth US$1 million, by the Gates Foundation. The Calestous Juma Science Leadership Fellowship, is for research into the "Great Obstetrical Syndromes"(GOS), including intrauterine growth retardation, stillbirth, preterm birth, pre-eclampsia and eclampsia, among women of African descent.[6]

Selected publications

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  • Annettee Nakimuli; Olympe Chazara; Susan E Hiby; et al. (5 January 2015). "A KIR B centromeric region present in Africans but not Europeans protects pregnant women from pre-eclampsia". Proceedings of the National Academy of Sciences of the United States of America. 112 (3): 845–850. Bibcode:2015PNAS..112..845N. doi:10.1073/PNAS.1413453112. ISSN 0027-8424. PMC 4311823. PMID 25561558. Wikidata Q35031374.
  • Voices from the frontline: findings from a thematic analysis of a rapid online global survey of maternal and newborn health professionals facing the COVID-19 pandemic. This study found substantial knowledge gaps exist in guidance on management of maternity cases with or without COVID-19.[7]
  • Male involvement during pregnancy and childbirth: men’s perceptions, practices and experiences during the care for women who developed childbirth complications in Mulago Hospital, Uganda. This study generated information on perceived roles, expectations, experiences and challenges faced by men who wish to be involved in maternal health issues, particularly during pregnancy and childbirth.[8]
  • A Risk prediction model for the assessment and triage of women with hypertensive disorders of pregnancy in low-resourced settings: The miniPIERS (Pre-eclampsia Integrated Estimate of RiSk) multi-country prospective cohort study. The article found reasonable ability to identify women at increased risk of adverse maternal outcomes associated with the hypertensive disorders of pregnancy.[9]
  • Indirect effects of COVID-19 on maternal, neonatal, child, sexual and reproductive health services in Kampala, Uganda.[10]
  • Protecting hard-won gains for mothers and newborns in low-income and middle-income countries in the face of COVID-19: call for a service safety net. The study suggested that providing adequate funding to maintain essential services alongside urgent action plans for COVID-19 is essential to enable rapid adaptation and modifications to service delivery in response to different transmission scenarios and stages of the pandemic.[11]
  • Pregnancy, parturition and preeclampsia in women of African ancestry. Among others the study suggested that there are particularly strong evolutionary selective pressures operating during pregnancy and delivery in Africans.[12]
  • Does knowledge of danger signs of pregnancy predict birth preparedness? A critique of the evidence from women admitted with pregnancy complications. The study emphasized the need to prioritize emergency/complication readiness during antenatal care sessions.[13]
  • Still births, neonatal deaths and neonatal near miss cases attributable to severe obstetric complications: a prospective cohort study in two referral hospitals in Uganda. This study established that antepartum hemorrhage, ruptured uterus, severe preeclampsia, eclampsia, and the syndrome of Hemolysis, Elevated Liver Enzymes, Low Platelets (HELLP syndrome), led to statistically significant attributable risk of newborn deaths (still birth or neonatal deaths).[14]
  • Maternal near misses from two referral hospitals in Uganda: a prospective cohort study on incidence, determinants and prognostic factors.[15]
  • The burden of maternal morbidity and mortality attributable to hypertensive disorders in pregnancy: a prospective cohort study from Uganda.[16]
  • ‘We are not going to shut down, because we cannot postpone pregnancy’: a mixed-methods study of the provision of maternal healthcare in six referral maternity wards in four sub-Saharan African countries during the COVID-19 pandemic.[17]
  • KIR2DS5 allotypes that recognize the C2 epitope of HLA-C are common among Africans and absent from Europeans. This study found that KIR2DS5*005 has the KIR2DS5 consensus sequence and was the only allele found at both centromeric and telomeric locations of KIR2DS5.[18]
  • Variations in killer-cell immunoglobulin-like receptor and human leukocyte antigen genes and immunity to malaria.[19]
  • Effect of a novel vital sign device on maternal mortality and morbidity in low-resource settings: a pragmatic, stepped-wedge, cluster-randomised controlled trial.[20]
  • Time trends in and factors associated with repeat adolescent birth in Uganda: Analysis of six demographic and health surveys.[21]
  • Relative impact of pre-eclampsia on birth weight in a low resource setting: A prospective cohort study.[22]

See also

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References

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  1. ^ Brenda Namatta (8 February 2021). "Dr. Nakimuli Takes Over Leadership of School of Medicine". Kampala: Makerere University School of Medicine. Archived from the original on 23 July 2021. Retrieved 20 April 2021.
  2. ^ "ECSACOG Council – ECSACOG". Retrieved 19 January 2023.
  3. ^ a b c d e f Makerere Medical School (March 2021). "Biography of Dr. Annet Olivia Nakimuli". Kampala: Makerere University School of Medicine. Archived from the original on 26 September 2021. Retrieved 20 April 2021.
  4. ^ Annet Olivia Nakimuli (2015). "Dr Annettee Olivia Nakimuli PhD Defence: The Role of Natural Killer Cells in Pre-eclampsia in an African Population". Kampala: Makerere University. Archived from the original on 12 January 2023. Retrieved 20 April 2021.
  5. ^ "Scopus preview - Nakimuli, Annettee - Author details - Scopus". www.scopus.com. Retrieved 19 January 2023.
  6. ^ Zaam Ssali (26 November 2021). "Assoc. Prof. Annettee Nakimuli wins US$1M grant for Maternal Health Research". Makerere University. Kampala, Uganda. Retrieved 2 December 2021.
  7. ^ Semaan, Aline; Audet, Constance; Huysmans, Elise; Afolabi, Bosede; Assarag, Bouchra; Banke-Thomas, Aduragbemi; Blencowe, Hannah; Caluwaerts, Séverine; Campbell, Oona Maeve Renee; Cavallaro, Francesca L.; Chavane, Leonardo; Day, Louise Tina; Delamou, Alexandre; Delvaux, Therese; Graham, Wendy Jane (1 June 2020). "Voices from the frontline: findings from a thematic analysis of a rapid online global survey of maternal and newborn health professionals facing the COVID-19 pandemic". BMJ Global Health. 5 (6): e002967. doi:10.1136/bmjgh-2020-002967. ISSN 2059-7908. PMC 7335688. PMID 32586891. S2CID 218580254.
  8. ^ Kaye, Dan K.; Kakaire, Othman; Nakimuli, Annettee; Osinde, Michael O.; Mbalinda, Scovia N.; Kakande, Nelson (31 January 2014). "Male involvement during pregnancy and childbirth: men's perceptions, practices and experiences during the care for women who developed childbirth complications in Mulago Hospital, Uganda". BMC Pregnancy and Childbirth. 14 (1): 54. doi:10.1186/1471-2393-14-54. ISSN 1471-2393. PMC 3916059. PMID 24479421.
  9. ^ Payne, Beth A.; Hutcheon, Jennifer A.; Ansermino, J. Mark; Hall, David R.; Bhutta, Zulfiqar A.; Bhutta, Shereen Z.; Biryabarema, Christine; Grobman, William A.; Groen, Henk; Haniff, Farizah; Li, Jing; Magee, Laura A.; Merialdi, Mario; Nakimuli, Annettee; Qu, Ziguang (21 January 2014). "A Risk Prediction Model for the Assessment and Triage of Women with Hypertensive Disorders of Pregnancy in Low-Resourced Settings: The miniPIERS (Pre-eclampsia Integrated Estimate of RiSk) Multi-country Prospective Cohort Study". PLOS Medicine. 11 (1): e1001589. doi:10.1371/journal.pmed.1001589. ISSN 1549-1676. PMC 3897359. PMID 24465185.
  10. ^ Burt, Jessica Florence; Ouma, Joseph; Lubyayi, Lawrence; Amone, Alexander; Aol, Lorna; Sekikubo, Musa; Nakimuli, Annettee; Nakabembe, Eve; Mboizi, Robert; Musoke, Philippa; Kyohere, Mary; Lugolobi, Emily Namara; Khalil, Asma; Doare, Kirsty Le (1 August 2021). "Indirect effects of COVID-19 on maternal, neonatal, child, sexual and reproductive health services in Kampala, Uganda". BMJ Global Health. 6 (8): e006102. doi:10.1136/bmjgh-2021-006102. ISSN 2059-7908. PMC 8406460. PMID 34452941. S2CID 233393641.
  11. ^ Graham, Wendy Jane; Afolabi, Bosede; Benova, Lenka; Campbell, Oona Maeve Renee; Filippi, Veronique; Nakimuli, Annettee; Penn-Kekana, Loveday; Sharma, Gaurav; Okomo, Uduak; Valongueiro, Sandra; Waiswa, Peter; Ronsmans, Carine (1 June 2020). "Protecting hard-won gains for mothers and newborns in low-income and middle-income countries in the face of COVID-19: call for a service safety net". BMJ Global Health. 5 (6): e002754. doi:10.1136/bmjgh-2020-002754. ISSN 2059-7908. PMC 7298807. PMID 32499220. S2CID 219331698.
  12. ^ Nakimuli, Annettee; Chazara, Olympe; Byamugisha, Josaphat; Elliott, Alison M.; Kaleebu, Pontiano; Mirembe, Florence; Moffett, Ashley (1 June 2014). "Pregnancy, parturition and preeclampsia in women of African ancestry". American Journal of Obstetrics and Gynecology. 210 (6): 510–520.e1. doi:10.1016/j.ajog.2013.10.879. ISSN 0002-9378. PMC 4046649. PMID 24184340. S2CID 13902725.
  13. ^ Mbalinda, Scovia N.; Nakimuli, Annettee; Kakaire, Othman; Osinde, Michael O.; Kakande, Nelson; Kaye, Dan K. (9 October 2014). "Does knowledge of danger signs of pregnancy predict birth preparedness? A critique of the evidence from women admitted with pregnancy complications". Health Research Policy and Systems. 12 (1): 60. doi:10.1186/1478-4505-12-60. ISSN 1478-4505. PMC 4197291. PMID 25300499.
  14. ^ Nakimuli, Annettee; Mbalinda, Scovia N.; Nabirye, Rose C.; Kakaire, Othman; Nakubulwa, Sarah; Osinde, Michael O.; Kakande, Nelson; Kaye, Dan K. (17 April 2015). "Still births, neonatal deaths and neonatal near miss cases attributable to severe obstetric complications: a prospective cohort study in two referral hospitals in Uganda". BMC Pediatrics. 15 (1): 44. doi:10.1186/s12887-015-0362-3. ISSN 1471-2431. PMC 4416266. PMID 25928880.
  15. ^ Nakimuli, Annettee; Nakubulwa, Sarah; Kakaire, Othman; Osinde, Michael O.; Mbalinda, Scovia N.; Nabirye, Rose C.; Kakande, Nelson; Kaye, Dan K. (28 January 2016). "Maternal near misses from two referral hospitals in Uganda: a prospective cohort study on incidence, determinants and prognostic factors". BMC Pregnancy and Childbirth. 16 (1): 24. doi:10.1186/s12884-016-0811-5. ISSN 1471-2393. PMC 4731977. PMID 26821716.
  16. ^ Nakimuli, Annettee; Nakubulwa, Sarah; Kakaire, Othman; Osinde, Michael Odongo; Mbalinda, Scovia Nalugo; Kakande, Nelson; Nabirye, Rose Chalo; Kaye, Dan Kabonge (4 August 2016). "The burden of maternal morbidity and mortality attributable to hypertensive disorders in pregnancy: a prospective cohort study from Uganda". BMC Pregnancy and Childbirth. 16 (1): 205. doi:10.1186/s12884-016-1001-1. ISSN 1471-2393. PMC 4973370. PMID 27492552.
  17. ^ Semaan, Aline; Banke-Thomas, Aduragbemi; Amongin, Dinah; Babah, Ochuwa; Dioubate, Nafissatou; Kikula, Amani; Nakubulwa, Sarah; Ogein, Olubunmi; Adroma, Moses; Adiga, William Anzo; Diallo, Abdourahmane; Diallo, Lamine; Diallo, Mamadou Cellou; Maomou, Cécé; Mtinangi, Nathanael (1 February 2022). "'We are not going to shut down, because we cannot postpone pregnancy': a mixed-methods study of the provision of maternal healthcare in six referral maternity wards in four sub-Saharan African countries during the COVID-19 pandemic". BMJ Global Health. 7 (2): e008063. doi:10.1136/bmjgh-2021-008063. ISSN 2059-7908. PMC 8844957. PMID 35144921. S2CID 246749788.
  18. ^ Blokhuis, Jeroen H.; Hilton, Hugo G.; Guethlein, Lisbeth A.; Norman, Paul J.; Nemat-Gorgani, Neda; Nakimuli, Annettee; Chazara, Olympe; Moffett, Ashley; Parham, Peter (6 July 2017). "KIR2DS5 allotypes that recognize the C2 epitope of HLA-C are common among Africans and absent from Europeans". Immunity, Inflammation and Disease. 5 (4): 461–468. doi:10.1002/iid3.178. ISSN 2050-4527. PMC 5691316. PMID 28685972.
  19. ^ Tukwasibwe, Stephen; Nakimuli, Annettee; Traherne, James; Chazara, Olympe; Jayaraman, Jyothi; Trowsdale, John; Moffett, Ashley; Jagannathan, Prasanna; Rosenthal, Philip J.; Cose, Stephen; Colucci, Francesco (2020). "Variations in killer-cell immunoglobulin-like receptor and human leukocyte antigen genes and immunity to malaria". Cellular & Molecular Immunology. 17 (8): 799–806. doi:10.1038/s41423-020-0482-z. ISSN 2042-0226. PMC 7294524. PMID 32541835.
  20. ^ Vousden, Nicola; Lawley, Elodie; Nathan, Hannah L; Seed, Paul T; Gidiri, Muchabayiwa Francis; Goudar, Shivaprasad; Sandall, Jane; Chappell, Lucy C; Shennan, Andrew H; Kachinjika, Monice; Bukani, Doreen; Makwakwa, Jane; Makonyola, Grace; Brown, Adrian; Toussaint, Paul (1 March 2019). "Effect of a novel vital sign device on maternal mortality and morbidity in low-resource settings: a pragmatic, stepped-wedge, cluster-randomised controlled trial". The Lancet Global Health. 7 (3): e347–e356. doi:10.1016/S2214-109X(18)30526-6. ISSN 2214-109X. PMC 6379820. PMID 30784635.
  21. ^ Amongin, Dinah; Nakimuli, Annettee; Hanson, Claudia; Nakafeero, Mary; Kaharuza, Frank; Atuyambe, Lynn; Benova, Lenka (14 April 2020). "Time trends in and factors associated with repeat adolescent birth in Uganda: Analysis of six demographic and health surveys". PLOS ONE. 15 (4): e0231557. Bibcode:2020PLoSO..1531557A. doi:10.1371/journal.pone.0231557. ISSN 1932-6203. PMC 7156070. PMID 32287303.
  22. ^ Nakimuli, Annettee; Starling, Jennifer E.; Nakubulwa, Sarah; Namagembe, Imelda; Sekikubo, Musa; Nakabembe, Eve; Scott, James G.; Moffett, Ashley; Aiken, Catherine E (1 July 2020). "Relative impact of pre-eclampsia on birth weight in a low resource setting: A prospective cohort study". Pregnancy Hypertension. 21: 1–6. doi:10.1016/j.preghy.2020.04.002. ISSN 2210-7789. PMC 7450268. PMID 32330863. S2CID 216130715.
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