Ardoin may refer to:
- Amédé Ardoin (1898–1942), American Creole musician
- Danny Ardoin, American baseball player
- John Ardoin (1935–2001) American music critic
- Ronald Ardoin, American jockey
- Chris Ardoin, American zydeco accordionist
- Alphonse "Bois Sec" Ardoin (1915–2007), American Cajun accordionist
- Kyle Ardoin, Secretary of State of Louisiana