In enzymology, an arylalkyl acylamidase (EC 3.5.1.76) is an enzyme that catalyzes the chemical reaction

arylalkyl acylamidase
Identifiers
EC no.3.5.1.76
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
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PMCarticles
PubMedarticles
NCBIproteins
N-acetylarylalkylamine + H2O arylalkylamine + acetate

Thus, the two substrates of this enzyme are N-acetylarylalkylamine and H2O, whereas its two products are arylalkylamine and acetate.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is N-acetylarylalkylamine amidohydrolase. This enzyme is also called aralkyl acylamidase.

References

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  • Shimizu S, Ogawa J, Chung MC, Yamada H (1992). "Purification and characterization of a novel enzyme, arylalkyl acylamidase, from Pseudomonas putida Sc2". Eur. J. Biochem. 209 (1): 375–82. doi:10.1111/j.1432-1033.1992.tb17299.x. PMID 1396711.