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Asad Ullah Khan

Asad Ullah Khan is an Indian microbiologist, biochemist and a professor at the Interdisciplinary Biotechnology Unit of the Aligarh Muslim University. He is known for his studies on multidrug resistant clinical strains as well as for the first sighting in India of Aligarh super bug (NDM-4), a variant of New Delhi metallo-beta-lactamase 1 (NDM-1). He is an elected fellow of the Royal Society of Chemistry, the Biotech Research Society, India and the Indian Academy of Microbiological Sciences. The Department of Biotechnology of the Government of India awarded him the National Bioscience Award for Career Development, one of the highest Indian science awards, for his contributions to biosciences, in 2012.

Asad Ullah Khan
Born
Badaun, India
Alma mater
Known forDiscovery of Aligarh super bug in India
Awards
  • 2020 Om Prakash Bhasin Award for Science and Technology
  • 2020  Visitor's award 2019
  • 2014 AMU Outstanding Research Award
  • 2012  N-BIOS Prize
  • 2011 DBT CREST Award
  • 2010 AMU Active Teacher Award
  • 2009 AMI-ALEMBIC Award
  • 2006 AMI Young Scientist Award
Scientific career
Fields
Institutions

Biography

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Entrance to Aligarh Muslim University

Dr. Asad Ullah Khan did his undergraduate studies in chemistry and post-graduate studies in biotechnology at the Aligarh Muslim University (AMU) after which he pursued his doctoral studies at the International Centre for Genetic Engineering and Biotechnology, New Delhi to secure a PhD in biochemistry from Aligarh Muslim University.[1] He started his career as a lecturer at AMU in 1997 and during his career there, he did his post-doctoral studies at Rutgers University during 2000–03. He returned to India to resume his career at AMU where he holds the position of a professor and the coordinator of the Biotechnology Unit.[2]

Professional profile

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Klebsiella pneumoniae, the bacterium in which NDM-1 was first identified

Khan's research focus is on developing new inhibitors against multidrug resistant clinical strains with special interest on extended spectrum beta lactamases (ESBL) such as NDM-1 and CTX-M, using QSARR modeling and structure-based virtual screening methods.[1] The team led by him collect Escherichia coli and Klebsiella pneumoniae strains from hospital and community-acquired infection sites and it was during one of those explorations that he discovered a variant of New Delhi metallo-beta-lactamase 1 named NDM-4, more commonly known as Aligarh super bug, in the sewage drains of Jawaharlal Nehru Medical College, Aligarh, in 2014.[3][4] This was the first recorded sighting of the antibiotic-resistant super bug in India;[note 1][6][7] the finding was later disclosed by Khan in an article published in the Journal of Medical Microbiology.[8] Later, Khan and his colleagues developed a protocol for detecting super bugs and was successful in sequencing the genes of three variants of NDM-1.[9] His studies have been documented by way of a number of articles[10][note 2] and ResearchGate, an online repository of scientific articles has listed 241 of them.[11] Besides he has also edited three books.[2] Khan is a member of the scientific committee of the Indian Academy of Biomedical Sciences[12] and sits in the advisory board of the Sir Syed Global Scholar Award (SSGSA) committee.[13] He is an associate editor of BMC Microbiology for their section on Clinical microbiology and vaccines[14] and is a member of the Task Force on Bioinformatics, Computational and Systems Biology of the Department of Biotechnology.[2] He has also conducted workshops and seminars on the subject.[15]

Awards and honors

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Recipient of Sri Om Prakash Bhasin Award-2019 and visitor's Award 2019 for his trail-blazing research in Biotechnology; The Association of Microbiologists of India (AMI) awarded Khan the Young Scientist Award in 2006;[2] AMI honored him again in 2009 with the Alembic Award.[16][17] He received the Most Active Teacher Award from Aligarh Muslim University in 2010[18] and the Cutting-Edge Research Enhancement and Scientific Training (CREST) Award of the Department of Biotechnology in 2011.[2] The Department of Biotechnology (DBT) of the Government of India awarded him the National Bioscience Award for Career Development, one of the highest Indian science awards in 2012.[19] When Aligarh Muslim University instituted the Outstanding Research Award in 2014, he was the first recipient of the award.[20]

Khan was elected as a fellow by the Royal Society of Chemistry in 2017.[21] He is also an elected fellow of the Biotech Research Society, India[22] and the Indian Academy of Microbiological Sciences[23] and the various research fellowships he has received include University Grants Commission fellowship (1995–98), Boyscast fellowship of the Department of Science and Technology (2004–05) and the visiting fellowship of the Indian National Science Academy (2006–07).[20]

Selected bibliography

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See also

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Notes

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  1. ^ New Delhi metallo-beta-lactamase 1 was the first in the series of NDM super bugs and was detected in a Swedish patient in New Dehi in 2009,[5]
  2. ^ Please see Selected bibliography section

References

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  1. ^ a b "Asad U Khan Lab". Aligarh Muslim University India. 30 January 2018. Retrieved 30 January 2018.
  2. ^ a b c d e "Aligarh Muslim University - Department Page". www.amu.ac.in. 30 January 2018. Retrieved 30 January 2018.
  3. ^ Krishnan, Vidya (2 October 2014). "Why India should be worried about the Aligarh superbug". Live Mint. Retrieved 31 January 2018.
  4. ^ Rahman, SZ; Mishra, A (June 2017). "Discovery of Aligarh Super Bug and Widespread variants of NDM1: A concern in antimicrobial resistance (Editorial)". Bangladesh Journal of Medical Science. 16 (3): 335–336. doi:10.3329/bjms.v16i3.32842.
  5. ^ Yong, Dongeun; Toleman, Mark A.; Giske, Christian G.; Cho, Hyun S.; Sundman, Kristina; Lee, Kyungwon; Walsh, Timothy R. (1 December 2009). "Characterization of a New Metallo-β-Lactamase Gene, blaNDM-1, and a Novel Erythromycin Esterase Gene Carried on a Unique Genetic Structure in Klebsiella pneumoniae Sequence Type 14 from India". Antimicrobial Agents and Chemotherapy. 53 (12): 5046–5054. doi:10.1128/aac.00774-09. ISSN 0066-4804. PMC 2786356. PMID 19770275.
  6. ^ "New 'superbug' found in Aligarh hospital drain - Times of India". The Times of India. 5 September 2014. Retrieved 31 January 2018.
  7. ^ "Antibiotic Resistant 'Super Bug' Found at Aligarh Muslim University". NDTV.com. 3 September 2014. Retrieved 31 January 2018.
  8. ^ PTI (3 September 2014). "Antibiotic resistant 'superbug' found at Aligarh medical college". Live Mint. Retrieved 31 January 2018.
  9. ^ "AMU scientists 'develop' technique to detect superbug". The Hindu. 10 June 2011. ISSN 0971-751X. Retrieved 31 January 2018.
  10. ^ "On Google Scholar". Google Scholar. 30 January 2018. Retrieved 30 January 2018.
  11. ^ "On ResearchGate". 30 January 2018. Retrieved 30 January 2018.
  12. ^ "Welcome to :: Indian Academy of Biomedical Sciences (IABS) - Uttar Pradesh, India". iabs.in. 30 January 2018. Archived from the original on 8 June 2017. Retrieved 30 January 2018.
  13. ^ "Sir Syed Global Scholar Award (SSESA)". www.ssgsa.us. 30 January 2018. Retrieved 30 January 2018.[permanent dead link‍]
  14. ^ "BMC Microbiology". BMC Microbiology. 31 January 2018. Retrieved 31 January 2018.
  15. ^ "Centre For Sophisticated Instruments Facility AMU Organises Workshop On Flow Cytometry and Its Applications". myamu.in. 31 January 2018. Retrieved 31 January 2018.
  16. ^ "Awardees - Association of Microbiologists of India". www.amiindia.info. 31 January 2018. Retrieved 31 January 2018.
  17. ^ "Dr Asadullah Khan Awarded AMI-ALEMBIC Award of 2009". amunewsandviews.blogspot.ae. 31 January 2018. Retrieved 31 January 2018.
  18. ^ Reporter, ummid.com Staff. "Distinguished AMU research scholars, teachers and students honored". www.ummid.com. Retrieved 31 January 2018.
  19. ^ "Awardees of National Bioscience Awards for Career Development" (PDF). Department of Biotechnology. 2016. Archived from the original (PDF) on 4 March 2018. Retrieved 20 November 2017.
  20. ^ a b "National Fellowships and Awards". Interdisciplinary Biotechnology Unit Aligarh Muslim University India. 31 January 2018. Retrieved 31 January 2018.
  21. ^ "AMU Faculty elected as Fellow of Royal Society of Chemistry". Two Circles. 18 November 2017. Retrieved 31 January 2018.
  22. ^ "Fellows of BRSI". The Biotech Research Society, India. 31 January 2018. Retrieved 31 January 2018.
  23. ^ "AMI Fellows". Association of Microbiologists of India. 31 January 2018. Retrieved 31 January 2018.

Further reading

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