Asimilobine is an inhibitor of dopamine biosynthesis, and a serotonergic receptor antagonist.[2][3]
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Names | |
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IUPAC name
1-Methoxy-12-nor-6aβ-aporphin-2-ol
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Systematic IUPAC name
(6aS)-1-Methoxy-5,6,6a,7-tetrahydro-4H-benzo[i]perimidin-2-ol | |
Identifiers | |
3D model (JSmol)
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ChEMBL | |
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PubChem CID
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CompTox Dashboard (EPA)
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Properties | |
C17H17NO2 | |
Molar mass | 267.328 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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References
edit- ^ "KNApSAcK Metabolite Information - C00025231". www.knapsackfamily.com.
- ^ Shoji, N; Umeyama, A; Saito, N; Iuchi, A; Takemoto, T; Kajiwara, A; Ohizumi, Y (1987). "Asimilobine and lirinidine, serotonergic receptor antagonists, from Nelumbo nucifera". Journal of Natural Products. 50 (4): 773–4. doi:10.1021/np50052a044. PMID 3430176.
- ^ Jin, CM; Lee, JJ; Kim, YK; Ryu, SY; Lim, SC; Hwang, BY; Lee, CK; Lee, MK (2008). "Effects of asimilobine on dopamine biosynthesis and l-DOPA-induced cytotoxicity in PC12 cells". Journal of Asian Natural Products Research. 10 (7–8): 747–55. doi:10.1080/10286020802030892. PMID 18696327. S2CID 47473525.