Aspartate N-acetyltransferase

In enzymology, an aspartate N-acetyltransferase (EC 2.3.1.17) is an enzyme that catalyzes the chemical reaction

aspartate N-acetyltransferase
Identifiers
EC no.2.3.1.17
CAS no.9029-99-6
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins
acetyl-CoA + L-aspartate CoA + N-acetyl-L-aspartate

Thus, the two substrates of this enzyme are acetyl-CoA and L-aspartate, whereas its two products are CoA and N-acetyl-L-aspartate.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acetyl-CoA:L-aspartate N-acetyltransferase. Other names in common use include aspartate acetyltransferase, and L-aspartate N-acetyltransferase.

References

edit
  • Goldstein FB (1959). "Biosynthesis of N-acetyl-L-aspartic acid". J. Biol. Chem. 234: 2702–2706.
  • Knizley H (October 1967). "The enzymatic synthesis of N-acetyl-L-aspartic acid by a water-insoluble preparation of a cat brain acetone powder". The Journal of Biological Chemistry. 242 (20): 4619–22. PMID 6061408.