Aspoxicillin (trade name Doyle[1]) is an antibiotic drug of the beta-lactam class.[2] It is an injectable form of penicillin that is highly active against Gram-positive and Gram-negative bacteria, including Bacillus fragilis,[3] which is resistant to other beta-lactam antibiotics.[4] It is approved for use in Japan.[1]
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Trade names | Doyle |
Other names | TA-058 |
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Formula | C21H27N5O7S |
Molar mass | 493.54 g·mol−1 |
References
edit- ^ a b "Aspoxicillin". IUPHAR/BPS Guide to Pharmacology.
- ^ Matsumoto K (July 1987). "[Review: New antimicrobial agent series XXII: Aspoxicillin]". The Japanese Journal of Antibiotics. 40 (7): 1221–1242. PMID 3316732.
- ^ "Aspoxicillin". Inxight Drugs. National Center for Advancing Translational Sciences.
- ^ Edwards R (December 1997). "Resistance to beta-lactam antibiotics in Bacteroides spp". Journal of Medical Microbiology. 46 (12): 979–986. doi:10.1099/00222615-46-12-979. PMID 9402919.