Avenue A may refer to:
- Avenue A (Brooklyn), in Canarsie, Brooklyn, New York City
- Avenue A (Manhattan), in Manhattan, New York City
- Avenue A (Saskatoon), a former name of an arterial road in Saskatoon, Saskatchewan, Canada, presently known as Idylwyld Drive
- Avenue A | Razorfish, an advertising agency, now Razorfish
- Avenue A, a song by Canadian rock music band Red Rider on their 1979 album Don't Fight It