Ayi is a unisex given name. Notable people with the name include:

  • Ayi Jihu (born 1984), Chinese singer
  • Ayi Kwei Armah (born 1939), Ghanaian writer
  • Ayi Sutarno (21st century), Indonesian tennis player
  • Vissinto Ayi d'Almeida (21st century), Beninese diplomat