Baruol synthase (EC 5.4.99.57, BARS1) is an enzyme with systematic name (3S)-2,3-epoxy-2,3-dihydrosqualene mutase (cyclizing, baruol-forming).[1] This enzyme catalyses the following chemical reaction
| Baruol synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 5.4.99.57 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
- (3S)-2,3-epoxy-2,3-dihydrosqualene baruol
The enzyme from Arabidopsis thaliana also produces traces of 22 other triterpenoids.
References
edit- ^ Lodeiro S, Xiong Q, Wilson WK, Kolesnikova MD, Onak CS, Matsuda SP (September 2007). "An oxidosqualene cyclase makes numerous products by diverse mechanisms: a challenge to prevailing concepts of triterpene biosynthesis". Journal of the American Chemical Society. 129 (36): 11213–22. doi:10.1021/ja073133u. PMID 17705488.
External links
edit- Baruol+synthase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
