Benzil reductase ((R)-benzoin forming)

Benzil reductase ((R)-benzoin forming) (EC 1.1.1.321) is an enzyme with systematic name (R)-benzoin:NADP+ oxidoreductase.[1] This enzyme catalyses the following chemical reaction

Benzil reductase ((R)-benzoin forming)
Identifiers
EC no.1.1.1.321
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Search
PMCarticles
PubMedarticles
NCBIproteins
(R)-benzoin + NADP+ benzil + NADPH + H+

The bacterial enzyme (Xanthomonas oryzae) enantioselectively reduces one of the two carbonyl groups of benzil to form optically active (R)-benzoin.

References

edit
  1. ^ Konishi J, Ohta H, Tuchihashi G (1985). "Asymmetric reduction of benzil to benzoin catalyzed by the enzyme system of a microorganism". Chem. Lett. 14: 1111–1112. doi:10.1246/cl.1985.1111.
edit