Benzylpenicilloyl polylysine (Pre-Pen) is used as a skin test before the administration of penicillin. It is used to detect the immunoglobulin E antibodies.[1][2] The chemical structure consists of the benzylpenicilloyl group attached to a polymer of L-lysine.[3][4][5]
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| Trade names | Pre-Pen |
| Other names | Pre-Pen |
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| Routes of administration | Liquid intradermal |
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References
edit- ^ "Benzylpenicilloyl polylysine". PharmGKB.
- ^ "Benzylpenicilloyl polylysine". DrugBank.
- ^ Vemuri P, Harris KE, Suh LA, Grammer LC (2004). "Preparation of benzylpenicilloyl-polylysine: a preliminary study". Allergy and Asthma Proceedings. 25 (3): 165–168. PMID 15317320.
- ^ Goldschmidt BM, Levine BB (June 1983). "The preparation and determination of structure of benzylpenicilloyl compounds used in skin-testing for penicillin allergy". The Journal of Antibiotics. 36 (6): 709–714. doi:10.7164/antibiotics.36.709. PMID 6874593.
- ^ "PRE-PEN® (benzylpenicilloyl polylysine injection USP) Skin Test Antigen". DailyMed. U.S. National Library of Medicine.