Berkeley is a surname. It is also used, uncommonly, as a given name. The name is a habitation name from Berkeley, Gloucestershire, England, itself derived from Old English beorce léah meaning birch lea. People with the name include:
- The Berkeley family of England
- Baron Berkeley
- Berkeley baronets
- Anne Berkeley, Baroness Berkeley, lady-in-waiting to Anne Boleyn, Henry VIII's second wife
- Elizabeth Berkeley, Countess of Ormond, wife of Thomas Butler, 10th Earl of Ormond and daughter of the above
- Lady Henrietta Berkeley (born c. 1664, died 1706)
- Anthony Berkeley Cox or Anthony Berkeley, writer
- Ballard Berkeley (1904–1988), English actor
- Busby Berkeley, film choreographer
- Edmund Berkeley (1909–1988), mathematician and computer scientist
- Elizabeth Berkeley (c1713-1799), wife of Charles Noel Somerset, 4th Duke of Beaufort
- George Berkeley (1685–1753), also known as Bishop Berkeley, Irish philosopher
- George Berkeley (died 1746) (1680–1746), MP for Dover 1720–1734
- Grantley Berkeley (1800–1881), British politician, writer
- Humphrey Berkeley (1926–1994), British politician
- John Berkeley, 1st Baron Berkeley of Stratton (1602–1678), English soldier
- John Berkeley, 3rd Baron Berkeley of Stratton (1663–1697), English admiral
- Jon Berkeley, author and illustrator
- Sir Lennox Berkeley (1903–1989), English composer
- Mary Berkeley (born 1965), English long jumper
- Mary Berkeley (courtier), alleged mistress of Henry VIII and mother of his son, John Perrot
- Matthew Berkeley (born 1987), English footballer
- Michael Berkeley (born 1948), British composer and broadcaster
- Miles Joseph Berkeley (1803–1889), English cryptogramist and clergyman
- Norborne Berkeley, 4th Baron Botetourt (1718–1770), Member of Parliament and governor of Virginia Colony
- Randolph Carter Berkeley, a United States Marine Corps major general who received the Medal of Honor for his actions during the United States occupation of Veracruz.
- Reginald Cheyne Berkeley (1890–1935), British Liberal Party Member of Parliament 1922–1924, then a playwright and scriptwriter
- Theresa Berkeley (died 1836), London dominatrix
- Sir William Berkeley (governor) (1605–1677), governor of Virginia
- Sir William Berkeley (Royal Navy officer) (1639–1666), English naval officer and admiral
- Vivian Berkeley (born 1941), blind Canadian lawn bowling champion and 1996 paralympic silver medalist
- Xander Berkeley (born 1955), American actor