Bessho (written: 別所) is a Japanese surname. Notable people with the surname include:

  • Kimie Bessho (別所 キミヱ, born 1947), Japanese para table tennis player
  • Koro Bessho (別所 浩郎, born 1953), Japanese diplomat
  • Nagaharu Bessho (別所 長治, 1558–1580), Japanese daimyō
  • Takehiko Bessho (別所 毅彦, 1922–1999), Japanese baseball player
  • Tetsuya Bessho (別所 哲也, born 1965), Japanese actor and radio presenter
  • Yoshiyo Bessho (別所 吉代, 1904–2018), Japanese supercentenarian