Beta-alanopine dehydrogenase

Beta-alanopine dehydrogenase (EC 1.5.1.26) is an enzyme that catalyzes the chemical reaction

beta-alanopine dehydrogenase
Identifiers
EC no.1.5.1.26
CAS no.113573-64-1
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins
beta-alanopine + NAD+ + H2O beta-alanine + pyruvate + NADH + H+

The 3 substrates of this enzyme are beta-alanopine, nicotinamide adenine dinucleotide ion, and water, whereas its 4 products are beta-alanine, pyruvate, nicotinamide adenine dinucleotide, and hydrogen ion.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH group of donors with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is N-(D-1-carboxyethyl)-beta-alanine:NAD+ oxidoreductase (beta-alanine-forming).

References

edit
  • Sato M, Takahara M, Kanno N, Sato Y, Ellington WR (1987). "Isolation of a new opine, beta-alanopine, from the extracts of the muscle of the marine bivalve mollusc Scapharca broughtonii". Comp. Biochem. Physiol. 88B: 803–806.