Bicyclogermacrene synthase

Bicyclogermacrene synthase (EC 4.2.3.100, Ov-TPS4) is an enzyme with systematic name (2E,6E))-farnesyl-diphosphate diphosphate-lyase (bicyclogermacrene-forming).[1] This enzyme catalyses the following chemical reaction

Bicyclogermacrene synthase
Identifiers
EC no.4.2.3.100
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Search
PMCarticles
PubMedarticles
NCBIproteins
(2E,6E)-farnesyl diphosphate bicyclogermacrene + diphosphate

The enzyme from oregano (Origanum vulgare) gives mainly bicyclogermacrene with Mn2+ as a cofactor.

References

edit
  1. ^ Crocoll C, Asbach J, Novak J, Gershenzon J, Degenhardt J (August 2010). "Terpene synthases of oregano (Origanum vulgare L.) and their roles in the pathway and regulation of terpene biosynthesis". Plant Molecular Biology. 73 (6): 587–603. doi:10.1007/s11103-010-9636-1. hdl:11858/00-001M-0000-0012-A513-2. PMID 20419468. S2CID 45230098.
edit