Bicyclogermacrene synthase (EC 4.2.3.100, Ov-TPS4) is an enzyme with systematic name (2E,6E))-farnesyl-diphosphate diphosphate-lyase (bicyclogermacrene-forming).[1] This enzyme catalyses the following chemical reaction
| Bicyclogermacrene synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 4.2.3.100 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
- (2E,6E)-farnesyl diphosphate bicyclogermacrene + diphosphate
The enzyme from oregano (Origanum vulgare) gives mainly bicyclogermacrene with Mn2+ as a cofactor.
References
edit- ^ Crocoll C, Asbach J, Novak J, Gershenzon J, Degenhardt J (August 2010). "Terpene synthases of oregano (Origanum vulgare L.) and their roles in the pathway and regulation of terpene biosynthesis". Plant Molecular Biology. 73 (6): 587–603. doi:10.1007/s11103-010-9636-1. hdl:11858/00-001M-0000-0012-A513-2. PMID 20419468. S2CID 45230098.
External links
edit- Bicyclogermacrene+synthase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
