In enzymology, a bile-acid-CoA hydrolase (EC 3.1.2.26) is an enzyme that catalyzes the chemical reaction
| Bile-acid-CoA hydrolase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 3.1.2.26 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
- deoxycholoyl-CoA + H2O CoA + deoxycholate
Thus, the two substrates of this enzyme are deoxycholoyl-CoA and H2O, whereas its two products are CoA and deoxycholate.
This enzyme belongs to the family of hydrolases, specifically those acting on thioester bonds. The systematic name of this enzyme class is deoxycholoyl-CoA hydrolase.
References
edit- Ye HQ, Mallonee DH, Wells JE, Bjorkhem I, Hylemon PB (1999). "The bile acid-inducible baiF gene from Eubacterium sp. strain VPI 12708 encodes a bile acid-coenzyme A hydrolase". J. Lipid Res. 40 (1): 17–23. PMID 9869646.
