Blane is a given name. Notable people with the name include:
- Blane Comstock (born 1949), American ice hockey player
- Blane De St. Croix, American artist
- Blane Gaison (born 1958), American football player
- M. Blane Michael, (1943–2011), American judge
- Blane Morgan (born 1977), American football coach
- Blane David Nordahl (born 1962), American cat burglar
- Blane Smith (born 1954), American football player
- Saint Blane, Scottish bishop and confessor
- Blane Muise, English musician
Fictional characters named Blane include:
- Blane McDonnagh, a character portrayed by Andrew McCarthy in Pretty in Pink