A blank value in analytical chemistry is a measurement of a blank. The reading does not originate from a sample, but the matrix effects, reagents and other residues. These contribute to the sample value in the analytical measurement and therefore have to be subtracted.[1]
The limit of blank is defined by the Clinical And Laboratory Standards Institute as the highest apparent analyte concentration expected to be found when replicates of a sample containing no analyte are tested.[2]
See also
editReferences
edit- ^ IUPAC, Compendium of Chemical Terminology, 2nd ed. (the "Gold Book") (1997). Online corrected version: (2006–) "blank value". doi:10.1351/goldbook.B00679
- ^ Armbruster DA, Pry T (2008). "Limit of blank, limit of detection and limit of quantitation". Clin Biochem Rev. 29 (Suppl 1): S49-52. PMC 2556583. PMID 18852857.
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