Buthalital

Buthalital
Clinical data
ATC code	None;
Identifiers
	IUPAC name sodium 5-allyl-5-isobutyl-6-oxo-2-thioxo-1,2,5,6-tetrahydro-4-pyrimidinolate;
CAS Number	510-90-7 ; 468-65-5 (no salt);
PubChem CID	3032320;
ChemSpider	2297324;
UNII	810E8N9VUG;
ChEMBL	ChEMBL2106716;
CompTox Dashboard (EPA)	DTXSID40965285 ;
Chemical and physical data
Formula	C11H15N2NaO2S
Molar mass	262.30 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES [Na+].O=C1NC(=S)/N=C(/[O-])C1(CC(C)C)C\C=C;
	InChI InChI=1S/C11H16N2O2S.Na/c1-4-5-11(6-7(2)3)8(14)12-10(16)13-9(11)15;/h4,7H,1,5-6H2,2-3H3,(H2,12,13,14,15,16);/q;+1/p-1; Key:APSWQQYXFMUODF-UHFFFAOYSA-M;

Buthalital sodium (INN; Bayinal, Baytinal, Thialbutal, Transithal, Ulbreval), or buthalitone sodium (BAN), is a barbiturate derivative which was under development as a short-acting anesthetic.^[1]^[2] However, development was discontinued, perhaps due to its extremely rapid elimination rate,^[3] and buthalital sodium was never marketed.^[1]

References

^ ^a ^b Macdonald F (1997). Dictionary of Pharmacological Agents. CRC Press. p. 338. ISBN 978-0-412-46630-4. Retrieved 19 May 2012.
^ Martin JR, Godel T, Hunkeler W, Jenck F, Moreau JL, Sleight AJ, Widmer U (2000). "Psychopharmacological Agents". Kirk-Othmer Encyclopedia of Chemical Technology. doi:10.1002/0471238961.1619250313011820.a01. ISBN 0471238961.
^ Wollweber H (2000). "Anesthetics, General". Ullmann's Encyclopedia of Industrial Chemistry. Weinheim: Wiley-VCH. doi:10.1002/14356007.a02_289. ISBN 978-3527306732.

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[Macdonald1997-1] Macdonald F (1997). Dictionary of Pharmacological Agents. CRC Press. p. 338. ISBN 978-0-412-46630-4. Retrieved 19 May 2012.

[MartinGodel2000-2] Martin JR, Godel T, Hunkeler W, Jenck F, Moreau JL, Sleight AJ, Widmer U (2000). "Psychopharmacological Agents". Kirk-Othmer Encyclopedia of Chemical Technology. doi:10.1002/0471238961.1619250313011820.a01. ISBN 0471238961.

[Wollweber2000-3] Wollweber H (2000). "Anesthetics, General". Ullmann's Encyclopedia of Industrial Chemistry. Weinheim: Wiley-VCH. doi:10.1002/14356007.a02_289. ISBN 978-3527306732.

[1]

[2]

[3]

Clinical data

ATC code	None
Identifiers
IUPAC name sodium 5-allyl-5-isobutyl-6-oxo-2-thioxo-1,2,5,6-tetrahydro-4-pyrimidinolate
CAS Number	510-90-7 468-65-5 (no salt)
PubChem CID	3032320
ChemSpider	2297324
UNII	810E8N9VUG
ChEMBL	ChEMBL2106716
CompTox Dashboard (EPA)	DTXSID40965285
Chemical and physical data
Formula	C₁₁H₁₅N₂NaO₂S
Molar mass	262.30 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES [Na+].O=C1NC(=S)/N=C(/[O-])C1(CC(C)C)C\C=C
InChI InChI=1S/C11H16N2O2S.Na/c1-4-5-11(6-7(2)3)8(14)12-10(16)13-9(11)15;/h4,7H,1,5-6H2,2-3H3,(H2,12,13,14,15,16);/q;+1/p-1 Key:APSWQQYXFMUODF-UHFFFAOYSA-M

Buthalital

See also

References