Byzantine Syrmia may refer to:
- Pannonia (Byzantine province) (567-582), first rule of the Byzantine Empire in the region of Syrmia
- Sirmium (theme), second rule of the Byzantine Empire in the region of Syrmia, from c. 1018 to c. 1071
- Byzantine Syrmia (1167-1180), third rule of the Byzantine Empire in the region of Syrmia