CBB can stand for:
- Camp B'nai Brith of Montreal, a Jewish summer camp near Lantier, Quebec
- Camp B'nai Brith of Ottawa, a Jewish summer camp near Quyon, Quebec
- Campeonato Brasileiro de Basquete
- Canterbury-Bankstown Bulldogs, an Australian rugby league team
- CBB, an indicator for a capacitor of the polypropylene film capacitor type
- CBB, the IATA code for Jórge Wilstermann International Airport in Cochabamba, Bolivia
- CBB, the National Rail code for Carbis Bay railway station, Cornwall, UK
- CBB, the pinyin railway code for Chibi North railway station, Hubei, China
- CBB, the stock symbol for Cincinnati Bell on the New York Stock Exchange
- Central Bank of Bahrain
- Central Bank of Barbados
- Celebrity Big Brother, the title of many celebrity versions of reality television show Big Brother
- Celebrity Big Brother (British TV series), a British reality television show
- Chesapeake Bay Bridge, a bridge over the Chesapeake Bay in Maryland, United States
- Circular barbell, a design in body-piercing jewelry
- Colby-Bates-Bowdoin Consortium, an athletic association between Colby, Bates, and Bowdoin College in Maine
- Comedy Bang! Bang!, a podcast
- Comedy Bang! Bang! (TV series), a television adaptation
- Common Building Block, a cross-manufacturer set of standards for laptop components
- Connexion by Boeing, a mobile ISP formerly offered by Boeing
- Coomassie brilliant blue, a dye commonly used to stain proteins in certain gels
- Internet slang for "can't be bothered" and "could be better"