CDP-archaeol synthase (EC 2.7.7.67, CDP-2,3-di-O-geranylgeranyl-sn-glycerol synthase, CTP:2,3-GG-GP ether cytidylyltransferase, CTP:2,3-di-O-geranylgeranyl-sn-glycero-1-phosphate cytidyltransferase) is an enzyme with systematic name CTP:2,3-bis-O-(geranylgeranyl)-sn-glycero-1-phosphate cytidylyltransferase.[1][2] This enzyme catalyses the following chemical reaction
| CDP-archaeol synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.7.7.67 | ||||||||
| CAS no. | 329791-09-5 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
- CTP + 2,3-bis-O-(geranylgeranyl)-sn-glycero-1-phosphate diphosphate + CDP-2,3-bis-O-(geranylgeranyl)-sn-glycerol
This enzyme catalyses one of the steps in the biosynthesis of polar lipids in Archaea.
References
edit- ^ Morii H, Nishihara M, Koga Y (November 2000). "CTP:2,3-di-O-geranylgeranyl-sn-glycero-1-phosphate cytidyltransferase in the methanogenic archaeon Methanothermobacter thermoautotrophicus". The Journal of Biological Chemistry. 275 (47): 36568–74. doi:10.1074/jbc.m005925200. PMID 10960477.
- ^ Morii H, Koga Y (February 2003). "CDP-2,3-Di-O-geranylgeranyl-sn-glycerol:L-serine O-archaetidyltransferase (archaetidylserine synthase) in the methanogenic archaeon Methanothermobacter thermautotrophicus". Journal of Bacteriology. 185 (4): 1181–9. doi:10.1128/jb.185.4.1181-1189.2003. PMC 142863. PMID 12562787.
External links
edit- CDP-archaeol+synthase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
