CDP-paratose synthase (EC 1.1.1.342, rfbS (gene)) is an enzyme with systematic name CDP-alpha-D-paratose:NADP+ 4-oxidoreductase.[1][2] This enzyme catalyses the following chemical reaction
| CDP-paratose synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.1.1.342 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
- CDP-alpha-D-paratose + NADP+ CDP-4-dehydro-3,6-dideoxy-alpha-D-glucose + NADPH + H+
This enzyme participates in synthesis of paratose and tyvelose.
References
edit- ^ Verma N, Reeves P (October 1989). "Identification and sequence of rfbS and rfbE, which determine antigenic specificity of group A and group D salmonellae". Journal of Bacteriology. 171 (10): 5694–701. PMC 210416. PMID 2793833.
- ^ Hallis TM, Lei Y, Que NL, Liu H (April 1998). "Mechanistic studies of the biosynthesis of paratose: purification and characterization of CDP-paratose synthase". Biochemistry. 37 (14): 4935–45. doi:10.1021/bi9725529. PMID 9538012.
External links
edit- CDP-paratose+synthase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
