CEACAM16

CEACAM16
Identifiers
Aliases	CEACAM16, CEAL2, DFNA4B, carcinoembryonic antigen related cell adhesion molecule 16, DFNB113, CEA cell adhesion molecule 16, tectorial membrane component
External IDs	OMIM: 614591; MGI: 2685615; HomoloGene: 19857; GeneCards: CEACAM16; OMA:CEACAM16 - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	44,710,718 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	19,595,224 bp
RNA expression pattern
	Top expressed in
	mucosa of large intestine; ; body of pancreas; ; mucosa of transverse colon; ; right adrenal cortex; ; left adrenal cortex; ; liver; ; right lobe of liver; ; tonsil; ; skeletal muscle; ; muscle of leg;
	Top expressed in
	inner ear; ; granulocyte; ; blastocyst; ; spleen; ; cerebellar cortex; ; adrenal gland; ; thymus; ; hippocampus proper; ; hypothalamus; ; primary visual cortex;
	More reference expression data
	n/a
Gene ontology
Molecular function	identical protein binding;
Cellular component	stereocilium tip; extracellular region; extracellular space;
Biological process	hearing;
	Sources:Amigo / QuickGO
Orthologs
	388551
	330483
	ENSG00000213892
	ENSMUSG00000014686
	Q2WEN9
	E9QA28
	NM_001039213
	NM_001033419
	NP_001034302
	NP_001028591
	Wikidata
View/Edit Human	View/Edit Mouse

Carcinoembryonic antigen-related cell adhesion molecule 16 is encoded in the human by the CEACAM16 gene. It is a member of the carcinoembryonic antigen family, a cluster of genes on chromosome 19. CEACAM16 is a structure of the tectorial membrane involved in hearing at low and high frequencies. It is the only carcinoembryonic antigen found in the platypus.^[5] The protein is expressed in mammalian outer hair cells, and mutations in this gene are associated with autosomal dominant nonsyndromic deafness.^[6]^[7]