CM156

CM156
Identifiers
	IUPAC name 3-[4-(4-cyclohexylpiperazin-1-yl)butyl]-1,3-benzothiazole-2-thione;
PubChem CID	17756659;
ChemSpider	23325411;
ChEMBL	ChEMBL272603;
CompTox Dashboard (EPA)	DTXSID301336011 ;
Chemical and physical data
Formula	C21H31N3S2
Molar mass	389.62 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES c1ccc2c(c1)n(c(=S)s2)CCCCN3CCN(CC3)C4CCCCC4;
	InChI InChI=1S/C21H31N3S2/c25-21-24(19-10-4-5-11-20(19)26-21)13-7-6-12-22-14-16-23(17-15-22)18-8-2-1-3-9-18/h4-5,10-11,18H,1-3,6-9,12-17H2; Key:FJGOTAJCEJCFEV-UHFFFAOYSA-N;

CM156^[1] is a piperazine based chemical compound with nanomolar affinity for both sigma receptor subtypes that has been shown to counteract the deleterious effects of administered cocaine.

References

^ Xu YT, Kaushal N, Shaikh J, Wilson LL, Mésangeau C, McCurdy CR, Matsumoto RR (May 2010). "A novel substituted piperazine, CM156, attenuates the stimulant and toxic effects of cocaine in mice". The Journal of Pharmacology and Experimental Therapeutics. 333 (2): 491–500. doi:10.1124/jpet.109.161398. PMC 2872963. PMID 20100904.

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[XuKaushal2010-1] Xu YT, Kaushal N, Shaikh J, Wilson LL, Mésangeau C, McCurdy CR, Matsumoto RR (May 2010). "A novel substituted piperazine, CM156, attenuates the stimulant and toxic effects of cocaine in mice". The Journal of Pharmacology and Experimental Therapeutics. 333 (2): 491–500. doi:10.1124/jpet.109.161398. PMC 2872963. PMID 20100904.

[1]

Identifiers

IUPAC name 3-[4-(4-cyclohexylpiperazin-1-yl)butyl]-1,3-benzothiazole-2-thione
PubChem CID	17756659
ChemSpider	23325411
ChEMBL	ChEMBL272603
CompTox Dashboard (EPA)	DTXSID301336011
Chemical and physical data
Formula	C₂₁H₃₁N₃S₂
Molar mass	389.62 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES c1ccc2c(c1)n(c(=S)s2)CCCCN3CCN(CC3)C4CCCCC4
InChI InChI=1S/C21H31N3S2/c25-21-24(19-10-4-5-11-20(19)26-21)13-7-6-12-22-14-16-23(17-15-22)18-8-2-1-3-9-18/h4-5,10-11,18H,1-3,6-9,12-17H2 Key:FJGOTAJCEJCFEV-UHFFFAOYSA-N

CM156

See also

References