Contactin-associated protein-like 4 is a protein that in humans is encoded by the CNTNAP4 gene.[5][6]

CNTNAP4
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesCNTNAP4, CASPR4, contactin associated protein like 4, contactin associated protein family member 4
External IDsOMIM: 610518; MGI: 2183572; HomoloGene: 24912; GeneCards: CNTNAP4; OMA:CNTNAP4 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_130457

RefSeq (protein)

NP_569724

Location (UCSC)Chr 16: 76.28 – 76.56 MbChr 8: 113.3 – 113.61 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

This gene product belongs to the neurexin family, members of which function in the vertebrate nervous system as cell adhesion molecules and receptors. This protein, like other neurexin proteins, contains epidermal growth factor repeats and laminin G domains. In addition, it includes an F5/8 type C domain, discoidin/neuropilin- and fibrinogen-like domains, and thrombospondin N-terminal-like domains. Alternative splicing results in two transcript variants encoding different isoforms.[6]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000152910Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000031772Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Spiegel I, Salomon D, Erne B, Schaeren-Wiemers N, Peles E (Jul 2002). "Caspr3 and caspr4, two novel members of the caspr family are expressed in the nervous system and interact with PDZ domains". Mol Cell Neurosci. 20 (2): 283–97. doi:10.1006/mcne.2002.1110. PMID 12093160. S2CID 25024421.
  6. ^ a b "Entrez Gene: CNTNAP4 contactin associated protein-like 4".
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Further reading

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