CPD-1

CPD-1
Legal status
Legal status	In general: uncontrolled;
Identifiers
	IUPAC name (3S)-3-Methyl-1-[4-(trifluoromethyl)-1-benzofuran-7-yl]piperazine;
CAS Number	325145-37-7 ;
PubChem CID	9925822;
ChemSpider	8101457;
UNII	ZZ7JB9QBU3;
ChEMBL	ChEMBL2260570;
CompTox Dashboard (EPA)	DTXSID901336526 ;
Chemical and physical data
Formula	C14H15F3N2O
Molar mass	284.282 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES C[C@H]1CN(CCN1)C2=C3C(=C(C=C2)C(F)(F)F)C=CO3;
	InChI InChI=1S/C14H15F3N2O/c1-9-8-19(6-5-18-9)12-3-2-11(14(15,16)17)10-4-7-20-13(10)12/h2-4,7,9,18H,5-6,8H2,1H3/t9-/m0/s1; Key:RZSIBGYUCGYDKG-VIFPVBQESA-N;

CPD-1 (LS-193743) is a drug with a benzofuranyl piperazine structure, which acts as a potent and selective agonist for the 5-HT₂ receptor family, with highest affinity and full agonist efficacy at the 5-HT_2C subtype, and lower affinity and partial agonist action at the 5-HT_2A and 5-HT_2B subtypes.^[1]^[2]

References

^ Ahmed A, Choo H, Cho YS, Park WK, Pae AN (July 2009). "Identification of novel serotonin 2C receptor ligands by sequential virtual screening". Bioorganic & Medicinal Chemistry. 17 (13): 4559–68. doi:10.1016/j.bmc.2009.05.003. PMID 19464901.
^ Rodriguez MM, Overshiner C, Leander JD, Li X, Morrow D, Conway RG, et al. (2017). "Behavioral Effects of a Novel Benzofuranyl-Piperazine Serotonin-2C Receptor Agonist Suggest a Potential Therapeutic Application in the Treatment of Obsessive-Compulsive Disorder". Frontiers in Psychiatry. 8: 89. doi:10.3389/fpsyt.2017.00089. PMC 5438973. PMID 28588509.

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Legal status

Legal status	In general: uncontrolled
Identifiers
IUPAC name (3S)-3-Methyl-1-[4-(trifluoromethyl)-1-benzofuran-7-yl]piperazine
CAS Number	325145-37-7^Y
PubChem CID	9925822
ChemSpider	8101457
UNII	ZZ7JB9QBU3
ChEMBL	ChEMBL2260570
CompTox Dashboard (EPA)	DTXSID901336526
Chemical and physical data
Formula	C₁₄H₁₅F₃N₂O
Molar mass	284.282 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES C[C@H]1CN(CCN1)C2=C3C(=C(C=C2)C(F)(F)F)C=CO3
InChI InChI=1S/C14H15F3N2O/c1-9-8-19(6-5-18-9)12-3-2-11(14(15,16)17)10-4-7-20-13(10)12/h2-4,7,9,18H,5-6,8H2,1H3/t9-/m0/s1 Key:RZSIBGYUCGYDKG-VIFPVBQESA-N