Copine-6 is a protein that in humans is encoded by the CPNE6 gene.[5][6]

CPNE6
Identifiers
AliasesCPNE6, copine 6
External IDsOMIM: 605688; MGI: 1334445; HomoloGene: 81815; GeneCards: CPNE6; OMA:CPNE6 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001280558
NM_006032

NM_001136057
NM_001146183
NM_009947
NM_001360193

RefSeq (protein)

NP_001267487
NP_006023

NP_001129529
NP_001139655
NP_034077
NP_001347122

Location (UCSC)Chr 14: 24.07 – 24.08 MbChr 14: 55.75 – 55.75 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

This gene encodes a brain-specific member of the copine family, which is composed of calcium-dependent membrane-binding proteins. The gene product contains two N-terminal C2 domains, and one von Willebrand factor A domain. It may have a role in synaptic plasticity.[6]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000100884Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000022212Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Nakayama T, Yaoi T, Yasui M, Kuwajima G (Jul 1998). "N-copine: a novel two C2-domain-containing protein with neuronal activity-regulated expression". FEBS Lett. 428 (1–2): 80–4. doi:10.1016/S0014-5793(98)00497-9. PMID 9645480. S2CID 27969998.
  6. ^ a b "Entrez Gene: CPNE6 copine VI (neuronal)".
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Further reading

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