CTR9

RNA polymerase-associated protein CTR9 homolog is an enzyme that in humans is encoded by the CTR9 gene.

CTR9
Identifiers
Aliases	CTR9, SH2BP1, TSBP, p150, p150TSP, CTR9 homolog, Paf1/RNA polymerase II complex component
External IDs	OMIM: 609366; MGI: 109345; HomoloGene: 40668; GeneCards: CTR9; OMA:CTR9 - orthologs
Gene location (Human) Chr. Chromosome 11 (human) Band 11p15.4 Start 10,751,246 bp End 10,801,625 bp
Gene location (Mouse) Chr. Chromosome 7 (mouse) Band 7 E3|7 57.98 cM Start 110,628,158 bp End 110,655,584 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in corpus epididymis epithelium of nasopharynx palpebral conjunctiva bronchial epithelial cell germinal epithelium retinal pigment epithelium caput epididymis oral cavity jejunal mucosa tail of epididymis Top expressed in Rostral migratory stream neural layer of retina spermatocyte transitional epithelium of urinary bladder tail of embryo gastrula uterus spermatid genital tubercle epiblast More reference expression data BioGPS More reference expression data
Gene ontology Molecular function RNA polymerase II complex binding SH2 domain binding protein binding Cellular component nuclear speck nucleus nucleoplasm Cdc73/Paf1 complex Biological process histone monoubiquitination receptor signaling pathway via JAK-STAT negative regulation of mRNA polyadenylation regulation of transcription, DNA-templated histone H3-K4 trimethylation negative regulation of transcription by RNA polymerase II Wnt signaling pathway transcription, DNA-templated stem cell population maintenance interleukin-6-mediated signaling pathway endodermal cell fate commitment positive regulation of histone H3-K4 methylation inner cell mass cell differentiation trophectodermal cell differentiation positive regulation of histone H3-K79 methylation blastocyst growth histone H2B ubiquitination positive regulation of histone H2B ubiquitination cellular response to lipopolysaccharide negative regulation of myeloid cell differentiation regulation of genetic imprinting positive regulation of transcription elongation from RNA polymerase II promoter positive regulation of transcription by RNA polymerase II transcription by RNA polymerase II transcription elongation from RNA polymerase II promoter protein ubiquitination histone modification regulation of histone H3-K4 methylation blastocyst hatching Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 9646 22083 Ensembl ENSG00000198730 ENSMUSG00000005609 UniProt Q6PD62 Q62018 RefSeq (mRNA) NM_014633 NM_001346279 NM_009431 RefSeq (protein) NP_001333208 NP_055448 NP_033457 Location (UCSC) Chr 11: 10.75 – 10.8 Mb Chr 7: 110.63 – 110.66 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

External links

• Human CTR9 genome location and CTR9 gene details page in the UCSC Genome Browser.

Further reading

• Nakayama M, Kikuno R, Ohara O (2003). "Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs". Genome Res. 12 (11): 1773–84. doi:10.1101/gr.406902. PMC 187542. PMID 12421765.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Colland F, Jacq X, Trouplin V, et al. (2004). "Functional proteomics mapping of a human signaling pathway". Genome Res. 14 (7): 1324–32. doi:10.1101/gr.2334104. PMC 442148. PMID 15231748.
• Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. Bibcode:2004PNAS..10112130B. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Beausoleil SA, Villén J, Gerber SA, et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nat. Biotechnol. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID 16964243. S2CID 14294292.
• Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.