The Dod-13 gene in the worm Caenorhabditis elegans encoding a cytochrome p450 enzyme, which have steroid hydroxylase activity, with the CYP Symbol CYP35B1 (Cytochrome P450, family 35, member B1).[1] Dod-13 is downstream gene of Daf-16 influenced the lifespan of C. elegans.[2]
Cytochrome P450 Dod-13 | |||||||
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Identifiers | |||||||
Organism | |||||||
Symbol | Dod-13 | ||||||
Alt. symbols | CYP35B1 | ||||||
Entrez | 178803 | ||||||
HomoloGene | 116141 | ||||||
RefSeq (mRNA) | NM_001322546 | ||||||
UniProt | O44650 | ||||||
Other data | |||||||
Chromosome | V: 3.94 - 3.94 Mb | ||||||
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References
edit- ^ Iser WB, Wilson MA, Wood WH, Becker K, Wolkow CA (March 2011). "Co-regulation of the DAF-16 target gene, cyp-35B1/dod-13, by HSF-1 in C. elegans dauer larvae and daf-2 insulin pathway mutants". PLOS ONE. 6 (3): e17369. Bibcode:2011PLoSO...617369I. doi:10.1371/journal.pone.0017369. PMC 3052305. PMID 21408062.
- ^ Murphy CT, McCarroll SA, Bargmann CI, Fraser A, Kamath RS, Ahringer J, et al. (July 2003). "Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans". Nature. 424 (6946): 277–83. Bibcode:2003Natur.424..277M. doi:10.1038/nature01789. PMID 12845331. S2CID 4424249.