The caiA RNA motif is a conserved RNA structure that was discovered by bioinformatics.[1] caiA motifs are found in Clostridiales.

caiA
Consensus secondary structure and sequence conservation of caiA RNA
Identifiers
SymbolcaiA
RfamRF02934
Other data
RNA typeGene; sRNA
SOSO:0001263
PDB structuresPDBe

caiA RNAs are found upstream of genes whose protein products function as acyl CoA dehydrogenases, although in one case the annotated substrate is butyryl-CoA. caiA RNAs might regulate these genes (i.e. function as cis-regulatory elements), but it is also possible that their association with these genes is a coincidence.

References

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  1. ^ Weinberg Z, Lünse CE, Corbino KA, Ames TD, Nelson JW, Roth A, Perkins KR, Sherlock ME, Breaker RR (October 2017). "Detection of 224 candidate structured RNAs by comparative analysis of specific subsets of intergenic regions". Nucleic Acids Res. 45 (18): 10811–10823. doi:10.1093/nar/gkx699. PMC 5737381. PMID 28977401.