Carlos Serrano (born 1963) is a Colombian musician.
Carlos Serrano may also refer to:
- Carlos Gerardo Rodríguez Serrano (born 1985), Mexican footballer
- Carlos Garrido Serrano (born 1994), known as Carlos Garrido, Spanish footballer
- Carlos Serrano, a character in the TV series ReGenesis
- Carlos Serrano Zárate (born 1998), Columbian Paralympic swimmer