Carnitine 3-dehydrogenase

In enzymology, a carnitine 3-dehydrogenase (EC 1.1.1.108) is an enzyme that catalyzes the chemical reaction

carnitine 3-dehydrogenase
Identifiers
EC no.	1.1.1.108
CAS no.	9045-45-8
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

carnitine + NAD⁺ $\rightleftharpoons$ 3-dehydrocarnitine + NADH + H⁺

• 
  Carnitine
• 
  3-Dehydrocarnitine

Thus, the two substrates of this enzyme are carnitine and NAD⁺, whereas its 3 products are 3-dehydrocarnitine, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD⁺ or NADP⁺ as acceptor. The systematic name of this enzyme class is carnitine:NAD⁺ 3-oxidoreductase.

References

• Aurich H, Kleber HP, Sorger H, Tauchert H (1968). "Reinigung und Eigenschaften der Carnitindehydrogenase aus Pseudomonas aeruginosa" [Purification and properties of carnitine dehydrogenase from Pseudomonas aeruginosa]. Eur. J. Biochem. (in German). 6 (2): 196–201. doi:10.1111/j.1432-1033.1968.tb00437.x. PMID 4302217.
• Schopp W, Sorger H, Kleber HP, Aurich H (1969). "Kinetische Untersuchungen zum Reaktionsmechanismus der Carnitindehydrogenase aus Pseudomonas aeruginosa" [Kinetic studies of the reaction mechanism of carnitine dehydrogenase of Pseudomonas aeruginosa]. Eur. J. Biochem. (in German). 10 (1): 56–60. doi:10.1111/j.1432-1033.1969.tb00654.x. PMID 4310279.

External links

• carnitine+dehydrogenase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
• EC 1.1.1.108